Why CBD oil is for you.
Cannabidiol (CBD) has recently been included in the media and you may even have seen it as an extra booster for your smoothie or morning coffee after training. What is CBD exactly? Why is it suddenly so popular?
What is CBD oil?
CBD stands for cannabidiol. It is the second most common of the active ingredients of cannabis (marijuana).
Although CBD is an essential part of medicinal marijuana, it comes directly from the hemp plant, a cousin of the marijuana plant. The active substance in CBD oil is CBD.
Although CBD is a component of marijuana (one of hundreds), it does not in itself cause a ‘high’.
According to a report from the World Health Organization: “In people, CBD does not show any effects that indicate abuse or dependence potential …
To date, there are no indications of public health problems related to the use of pure CBD. ”
CBD is increasingly praised and investigated because of its positive effect on our health.
In addition to CBD, CBDa, CBC and CBG are also important components, each with their own specific properties.
Another known cannabinoid is tetrahydrocannabinol (THC).
This substance is found in weed and is known for its psychoactive effect, through which one experiences euphoric feelings (“high”).
What is the difference between CBD and THC?
There is still much confusion about what CBD is, with many people thinking that cannabis, hemp, marijuana, and THC (tetrahydrocannabinol) are the same. They are not.
Cannabis is a plant and there are two main types: Cannabis Indica and Cannabis Sativa. Although marijuana can be derived from both types, hemp only comes from the Cannabis Sativa family.
This means that although hemp and marijuana have a few things in common, there are notable differences, with the most crucial fact that hemp contains almost no THC, the chemical in marijuana that gives you a high.
In fact, according to the law, hemp should not contain more than 0.3 percent THC to be considered as hemp, otherwise federal law would lead growers to risk being prosecuted.
The most important active ingredient in hemp is CBD and CBD has no psychoactive properties.
Instead, CBD is credited with relieving anxiety, inflammation, insomnia and pain, although “credited” does not mean proven.
Because of the historic regulatory landscape, there are hardly any well-executed studies that support these claims, although research is expected to increase as laws make a distinction between hemp and marijuana.
Nowadays CBD seems to be in everything, from protein powders to analgesic plasters to products for menstrual pain.
But check those labels. Because CBD is a fairly bitter substance, many products contain large amounts of added sugar.
In addition, many of the claims about the benefits of CBD are questionable. Ultimately, you only get an expensive supplement with a lot of sugar that doesn’t do much.
There is a prescribed CBD oil that is considered an effective medicine for epilepsy, called Epidiolex.
However, further research is needed to determine whether CBD is safe and effective for other medical conditions. Other studies are currently investigating the benefits for Parkinson’s disease, schizophrenia, diabetes, multiple sclerosis and anxiety.
In addition to the medicinal use of CBD, hemp is also a great source for making 100% biodegradable, environmentally friendly products such as biofuel, building materials, clothing and paper.
What are the health benefits of CBD oil?
Many manufacturers of CBD oil products (cannabidiol) claim that CBD is effective in relieving anxiety, depression, pain, inflammation, improving sleep or having other health benefits.
However, there are very few well-conducted studies to support these claims, apart from the use of CBD in two rare and severe forms of epilepsy, the Lennox-Gastaut syndrome (LGS) and the Dravet syndrome.
Most published studies have used marijuana, a combination of CBD and THC (tetrahydrocannabinol), or only animals. Only a few have only performed on CBD.
More than 200 different substances (called cannabinoids) can be extracted from the cannabis plant; CBD and THC are just two of these substances.
In contrast to THC, CBD has no psychoactive properties and does not give you ‘high’.
There is no evidence that it has potential for abuse or dependence, and so far there is no evidence that it is associated with serious side effects, according to the World Health Organization.
The main reason that there are few studies to support the perceived health benefits of CBD is that earlier laws have collected marijuana and hemp together in the same basket.
However, in December 2015, the FDA eased the legal requirements for CBD, allowing more CBD research, and investigations are now underway to investigate the benefits for Parkinson’s disease, schizophrenia, diabetes, multiple sclerosis, and anxiety.
The government’s position on CBD remains confusing, despite all 50 states that legalize CBD with varying degrees of limitation.
In summary, the only proven health benefit for CBD current is for Lennox-Gastaut syndrome (LGS) and Dravet syndrome (two forms of epilepsy).
Other possible health benefits for CBD (these need to be further investigated) include relief from:
- Arthritis pain
- Inflammation pain
- Muscle spasticity in multiple sclerosis
- Nausea and vomiting associated with cancer
- Nerve-related pain
- Sleep problems.
Because CBD is currently being marketed as a supplement, it is not regulated for safety and purity.
This means that you are not sure whether the product you buy contains CBD in the stated dosage, or whether it contains other (unlisted) ingredients.
Because CBD research is scarce, nobody really knows the most effective therapeutic dose of CBD for any medical condition.
For the consumer
Applies to cannabidiol: drink
In addition to the required effects, cannabidiol can cause some undesirable effects. Although not all of these side effects can occur, they may need medical attention if they occur.
Contact your doctor immediately if any of the following side effects occur while taking cannabidiol:
- lower back or side pain
- painful or difficult to urinate
- unusual sleepiness, dullness, tiredness, weakness or a slow feeling
- blue lips, fingernails or skin
- difficult or difficult breathing
- fast heartbeat
- irregular, fast or slow or superficial breathing
- loss of appetite
- stomach ache
Some side effects of cannabidiol can occur that do not usually require medical attention.
These side effects may disappear during treatment if your body adjusts to the medicine. Your healthcare provider may also tell you about ways to prevent or reduce some of these side effects.
Contact your doctor if any of the following side effects persist or are bothersome or if you have questions about it:
– Decreased appetite – Lack
of or loss of strength –
– Change in walking and balance –
clumsiness or instability –
decreased weight –
For healthcare professionals
Applies to cannabidiol: oral fluid
The more commonly reported side effects are drowsiness, decreased appetite, diarrhea, transaminase increases, skin rashes and insomnia
Very common (10% or more): increased liver transaminases (up to 16%)
In clinical studies, 13% of drug-treated patients experienced an increase in liver transaminase by more than three times the upper limit of normal (3 x ULN) compared to 1% in placebo patients.
Less than 1% had elevations greater than 20 x ULN. The majority of ALT increases occurred in patients taking valproate and / or clobazam simultaneously (30% using valproate and clobazam simultaneously; 21% simultaneously valproate and 4% clobazam simultaneously).
Only 3% of transaminase elevations occurred in patients using neither valproate nor clobazam.
Transaminase increases were dose dependent. ALT increases higher than 3 x ULN occurred in 17% of patients taking 20 mg / kg / day, compared to 1% in patients taking 10 mg / kg / day.
Patients with baseline transaminase elevations above ULN had higher rates of treatment-emergent ALT elevations.
In patients taking 20 mg / kg / day, ALT increases to more than 3 x ULN occurred in 30% of patients with ALT increases at baseline compared to 12% in patients whose ALT values were within the normal range at baseline.
Common (1% to 10%): insomnia, sleep disorder, poor sleep, irritability, agitation, aggression, anger
Very common (10% or more): sleepiness (up to 25%)
Common (1% to 10%): Sedation, lethargy, walking disorders [Ref]
Sleepiness and sedation (including lethargy) occurred in 32% of patients compared to 11% of those receiving placebo.
The number of cases was higher in patients with higher doses (34% versus 27% for doses of 20 mg / kg / day and 10 mg / kg / day, respectively). Incidents were even higher in patients taking clobazam concomitantly (46% versus 16%). [Ref]
Frequency not reported: hypersensitivity reaction (pruritus, erythema, angioedema) [Ref]
metabolic rate –
Common (1% to 10%): reduced weight [Ref]
Very common (10% or more): laboratory-defined anemia (30%) [Ref]
Mean decreases in hemoglobin (-0.42 g / dl) and hematocrit of (-1.5%) occurred in patients receiving this drug.
Thirty percent of patients developed a new laboratory-defined anemia during the clinical trial defined as a normal hemoglobin at baseline and a reported value lower than the lower limit of normal at a later time.
This is compared with 13% percent of placebo patients.
Very common (10% or more): viral infection (up to 11%), other infection (up to 21%)
Common (1% to 10%): fungal infection [Ref]
Common (1% to 10%): Pneumonia, hypoxia, respiratory failure [Ref]
Very common (10% or more): fatigue, malaise and asthenia (up to 12%) [Ref]
Frequency not reported: increase in creatinine
This drug increased serum creatinine in healthy adults and in patients with Lennox-Gastaut syndrome or Dravet syndrome.
An increase of approximately 10% was observed within 2 weeks of starting therapy. This increase was reversible in healthy adults.
Reversibility was not assessed in patients with Lennox-Gastaut syndrome or Dravet syndrome. The mechanism for this increase is unknown.
Very common (10% or more): result (up to 13%) [Ref]
Very common (10% or more): decreased appetite (up to 22%), diarrhea (up to 20%)
Common (1% to 10%): drooling, saliva hypersecretion, gastroenteritis, abdominal pain
Always consult your healthcare provider to ensure that the information on this page applies to your personal circumstances.
The evidence for the health benefits of cannabidiol
CBD has been touted for a wide range of health problems, but the strongest scientific evidence is its effectiveness in treating some of the cruelest epilepsy syndromes in children, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS), which are usually not react to counteract medication.
In many studies, CBD was able to reduce the number of attacks and in some cases it was able to stop them altogether.
Videos of the effects of CBD on these children and their attacks are readily available on the internet for viewing, and they are quite striking.
Recently, the FDA approved the first cannabis-derived drug for these conditions, Epidiolex, which contains CBD.
CBD is often used to address anxiety and for patients suffering from the misery of insomnia, studies suggest that CBD can help both fall asleep and stay asleep.
CBD can offer an option for treating various types of chronic pain.
A study by the European Journal of Pain showed that CBD on the skin using an animal model could help reduce pain and inflammation caused by arthritis.
Another study showed the mechanism by which CBD inhibits inflammatory and neuropathic pain, two of the most difficult forms of chronic pain to treat.
More human research is needed in this area to support CBD supporters’ claims about pain relief.
Is cannabidiol safe?
Side effects of CBD include nausea, fatigue and irritability.
CBD can raise the blood thinner coumadin level in your blood, and it can raise levels of certain other medicines in your blood through the exact same mechanism that grapefruit juice does.
An important safety problem with CBD is that it is mainly sold and sold as a supplement, not a medicine.
Currently, the FDA does not regulate the safety and purity of dietary supplements.
So you cannot be sure that the product you are purchasing has active ingredients in the dose that is on the label.
Moreover, the product may contain other (unknown) elements. We also do not know the most effective therapeutic dose of CBD for a particular medical condition.
The bottom line on cannabidiol
Some CBD manufacturers have come under government supervision for wild, indefensible claims, so CBD is a cure for cancer, which it is not.
We need more research, but CBD can be an option for dealing with anxiety, insomnia and chronic pain.
We cannot establish effective doses without sufficient high-quality evidence in human studies, and because CBD is currently usually available as an unregulated supplement, it is difficult to know exactly what you are receiving.
If you decide to try CBD, talk to your doctor – just to make sure it doesn’t affect other medicines that you use.
Types of CBD Oil
CBD is available in various strengths , ranging from 1% to no less than 30%.
The most sold strength is the 5% isolate or 20% full spectrum, as various studies have shown that this is the most effective dosage.
A lower percentage is more advantageous, but due to the greater dilution, the active substance also decreases proportionally.
These are therefore particularly suitable for children and (pets) animals.
Bioavailability of CBD Oil
Depending on the type of CBD you use, there is a certain percentage of bioavailability that you will experience.
When you use a current product, you only absorb part of that CBD in your bloodstream.
CBD Plasters offer a very fast and even absorption through the skin.
Oral doses like with CBD Oil drops will take a little longer to be absorbed into the digestive tract, but they work pretty well.
Taking a CBD product under the tongue usually results in 20 to 30 percent absorption into the bloodstream.
How much CBD should you take?
Now that you know how long the effects of CBD last, you may wonder how much CBD you need to take to feel these desired effects.
Remember that CBD affects everyone differently and the ideal portions will vary enormously. As we said before, it’s best to give it some time.
Start by slowly taking a small portion (5-10 mg) and then work your way up over the course of a few weeks until you get to that place and feel the desired benefits.
CBD works differently for everyone, which will ultimately determine how long the effects last for them personally. The type of CBD product and how you use it also has an important influence on how long the CBD effects last.
In general, depending on the type of CBD product you use, the effects will last for 2 to 8 hours.
For those looking for an alternative therapy option, however, CBD shows great promise.
When any type of CBD oil is combined with positive lifestyle changes, there can be a greater synergistic effect.
When you are looking for CBD products, you will notice two major varieties on the market – full / broad-spectrum CBD and CBD isolate. There are more than 100 cannabinoids in cannabis.
Isolated CBD products are exactly as they sound and contain only one of those cannabinoids (CBD) in an isolated oil.
Although isolated oils are efficient, they are not the highest quality CBD products available. This is because CBD works better in combination with other cannabinoids. This is known as the ‘entourage effect’.
In full / broad-spectrum CBD products, the efficiency of CBD in your system is enhanced by:
30+ terpenes (including myrcene, eucalyptol, linalool and geraniol).
Omega fatty acids.
Buy CBD Oil?
By using full / broad spectrum CBD products, you get all the benefits of the cannabis plant, minus the THC.
For those new to the world of CBD, in addition to buying a high-quality product, it is important to optimize your dosage and delivery for the desired effect.
If you are not sure whether CBD Oil is a good combination with your current medication, consult your doctor BEFORE using CBD Oil!